Changchien C C, Wu K C, Eng H L
Department of Obstetrics & Gynecology, Chang Gung Memorial Hospital, Kaoshiung Taiwan, R.O.C.
Changgeng Yi Xue Za Zhi. 1993 Sep;16(3):207-12.
We report three cases of squamous cell carcinoma originating from ovarian dermoid cysts. All patients were postmenopausal with the chief complaints of lower abdominal pain and palpable masses found by themselves. Two of them had diabetes mellitus. The tumor sizes were all more than 10 cm. The diagnoses were made by histological examination of tissues removed at surgery. Two cases were categorized into the FIGO stage IIIc and one in stage Ia. Sonographic findings were characterized by a large adnexal mass with mixed components. An elevated serum squamous cell carcinoma antigen was found in the two cases of advanced stage and one of them also had an elevated serum CA-125 level. All reported cases were unilaterally involved without ascites at laparotomy, while omental lymph nodes metastases were noted in the two cases of advanced stage. One of the patients in the advanced stage died six months after surgery and radiation therapy due to recurrence. The other patient in the advanced stage refused further treatment even though recurrence was found five months after surgery and chemotherapy. There was no evidence of recurrence in the early stage case during the two years of follow-up.
我们报告了三例起源于卵巢皮样囊肿的鳞状细胞癌病例。所有患者均为绝经后女性，主要主诉为下腹部疼痛，且均自行发现可触及肿块。其中两例患有糖尿病。肿瘤大小均超过10厘米。通过手术切除组织的组织学检查做出诊断。两例被归类为国际妇产科联盟（FIGO）IIIc期，一例为Ia期。超声检查结果的特征为附件区有一个混合成分的大肿块。两例晚期病例血清鳞状细胞癌抗原升高，其中一例血清CA-125水平也升高。所有报告病例均为单侧受累，剖腹手术时无腹水，而两例晚期病例发现有网膜淋巴结转移。一名晚期患者在手术后接受放疗六个月后因复发死亡。另一名晚期患者尽管在手术后接受化疗五个月时发现复发，但拒绝进一步治疗。早期病例在两年的随访中无复发迹象。
