Kubová Z, Kuba M
Katedra normální fyziologie LF UK, Hradec Králové.
Cesk Oftalmol. 1993 Oct;49(5):278-85.
In 21 patients with unilateral retrobulbar neuritis the pattern reversal evoked potentials and motion-onset visual potentials were investigated with the aim to find out whether there is some difference in affection of pattern detecting (parvocellular) and motion detecting (magnocellular) visual pathways in this disease. The pattern reversal potentials were found to be abnormal in all 21 patients: they showed either significantly prolonged latencies and reduced amplitudes of the main positive P100 peak or no clear response (in one patient) upon the stimulation of the eye with neuritis. In contrast, the main negative peak of the motion-onset potentials was significantly delayed only in 15 patients and its amplitude was distinctly reduced only in 3 patients. The results indicate that in retrobulbar neuritis the pattern detecting nerve fibres from the central part of the retina (tested by reversal potentials) are affected earlier and to a greater extent than the more peripherally distributed motion detecting fibres (tested by motion-onset potentials).
对21例单侧球后视神经炎患者的图形翻转诱发电位和运动起始视觉电位进行了研究，目的是了解在这种疾病中，图形检测（小细胞性）和运动检测（大细胞性）视觉通路的受累情况是否存在差异。发现所有21例患者的图形翻转电位均异常：它们要么显示主要正向P100波峰的潜伏期显著延长和波幅降低，要么在刺激患眼时（1例患者）无明确反应。相比之下，运动起始电位的主要负向波峰仅在15例患者中显著延迟，其波幅仅在3例患者中明显降低。结果表明，在球后视神经炎中，来自视网膜中央部分的图形检测神经纤维（通过翻转电位检测）比分布更外周的运动检测纤维（通过运动起始电位检测）更早且更严重地受到影响。
