使用计算机化姿势摆动测量系统评估接触锰的工人。

Use of a computerized postural sway measurement system for assessing workers exposed to manganese.

Chia S E, Goh J, Lee G, Foo S C, Gan S L, Bose K, Jeyaratnam J

Department of Community, Occupational and Family Medicine, National University of Singapore.

Clin Exp Pharmacol Physiol. 1993 Sep;20(9):549-53. doi: 10.1111/j.1440-1681.1993.tb01740.x.

Abstract

Computerized postural sway measurement systems have been used recently in human physiology and pharmacology for determining postural stability, but their applicability for the assessment of the effects of exposure to neurotoxic agents is lacking. 2. We have examined the feasibility of using a computerized postural sway measurement system to assess the postural sway parameters of manganese exposed workers compared with a control group. 3. Sway parameter data were collected using a KISLTER multicomponent measuring platform (Type 9281B) connected to VICON motion analysis system for 13 exposed and 16 control subjects. 4. Significant differences in several of the sway parameters (Px, Py--mean distance (mm), from the centre of the platform along the X-axis [anterior-posterior movement] and Y-axis [lateral movement], respectively) between the exposed and control groups were observed even after adjustment for possible confounders. Computerized postural sway measurement system may be a useful method of assessing workers exposed to neurotoxic agents affecting posture.

摘要

计算机化姿势摇摆测量系统最近已用于人类生理学和药理学中以确定姿势稳定性，但缺乏其在评估神经毒性剂暴露影响方面的适用性。2. 我们研究了使用计算机化姿势摇摆测量系统评估锰暴露工人与对照组相比的姿势摇摆参数的可行性。3. 使用连接到VICON运动分析系统的KISLTER多分量测量平台（9281B型）收集13名暴露组和16名对照组受试者的摇摆参数数据。4. 即使在对可能的混杂因素进行调整后，暴露组和对照组之间在几个摇摆参数（Px、Py——分别为沿平台X轴[前后运动]和Y轴[横向运动]距平台中心的平均距离（mm））上仍观察到显著差异。计算机化姿势摇摆测量系统可能是评估暴露于影响姿势的神经毒性剂的工人的一种有用方法。