Woodley D T, Chen J D, Kim J P, Sarret Y, Iwasaki T, Kim Y H, O'Keefe E J
Department of Dermatology, Northwestern University School of Medicine, Chicago, Illinois.
Dermatol Clin. 1993 Oct;11(4):641-6.
Keratinocyte migration and proliferation both play a role in covering skin wounds by the process of re-epithelialization. Connective tissue components are a powerful influence on keratinocyte locomotion. The mechanisms of keratinocyte locomotion and cellular division are independent. Both connective tissue components and soluble factors may serve to enhance keratinocyte migration. In addition to the field of growth factors, we would like to suggest that there should be the recognition of an entire new class of agents called migration factors.
角质形成细胞的迁移和增殖在通过再上皮化过程覆盖皮肤伤口中均发挥作用。结缔组织成分对角质形成细胞的移动有强大影响。角质形成细胞移动和细胞分裂的机制是独立的。结缔组织成分和可溶性因子均可促进角质形成细胞的迁移。除了生长因子领域，我们建议应该认识到一类全新的称为迁移因子的物质。
