[Long-term investigations of the influence of corticosteroids on lens transparency in rats (author's transl)].

Both a systemic cortisol treatment (10 mg/kg, daily, s.c.) for 275 days and a local administration of prednisolone eye drops (1%, 4 times daily) for 150 days failed to induce morphologic lens changes in wistar rats. Possible reasons for the different reactions to steroid treatment of human and animal lenses are discussed.