He Z Y, Li X K, Yu X J
Department of Hemorheology, Xinqiao Hospital, Third Military Medical College of PLA, Chongqing.
Chin Med J (Engl). 1993 Aug;106(8):601-3.
The relationship between cytosolic free [Ca2+]i and intracellular cAMP of platelet at various stages of experimental atherosclerosis in rabbits was studied. The results showed that the increase of [Ca2+]i was negatively correlated with the level of cAMP in cholesterol-fed rabbits (r = -0.667, P < 0.001) for 2, 4, 8 and 12 weeks. The viscosity of the whole blood at shear rates of 230.4/s and 5.76/s increased only in rabbits fed with cholesterol for 2 weeks, but the plasma viscosity increased in those fed for 2 and 4 weeks.
研究了兔实验性动脉粥样硬化不同阶段血小板胞浆游离钙离子浓度（[Ca2+]i）与细胞内环磷酸腺苷（cAMP）之间的关系。结果显示，在喂食胆固醇2周、4周、8周和12周的兔中，[Ca2+]i的升高与cAMP水平呈负相关（r = -0.667，P < 0.001）。仅在喂食胆固醇2周的兔中，剪切速率为230.4/s和5.76/s时全血黏度增加，但在喂食2周和4周的兔中血浆黏度增加。
