Wu H, Zhao H Y
Department of Internal Medicine, Tongji Hospital, Tongji Medical University, Wuhan.
Zhonghua Nei Ke Za Zhi. 1993 Mar;32(3):161-4.
A clinical study of intravenous captopril was performed in 10 patients with mild heart failure and 20 with severe heart failure. The results indicated that intravenous captopril may rapidly reduce cardiac preload and afterload, increase cardiac output, inhibit renin system activity and decrease plasma level of catecholamine. A short period of treatment with intravenous captopril may produce a rapid symptomatic improvement in patients with acute or severe heart failure. There was a good tolerance with the therapy.
对10例轻度心力衰竭患者和20例重度心力衰竭患者进行了静脉注射卡托普利的临床研究。结果表明，静脉注射卡托普利可迅速降低心脏前负荷和后负荷，增加心输出量，抑制肾素系统活性并降低血浆儿茶酚胺水平。静脉注射卡托普利进行短期治疗可使急性或重度心力衰竭患者的症状迅速改善。该疗法耐受性良好。
