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液氮冷冻手术在脊柱肿瘤手术治疗中的辅助应用

[The application of liquid nitrogen cryosurgery in adjuvant to surgical treatment of spinal tumor].

作者信息

Wu Q Q

机构信息

Beijing Tuberculosis and Chest Tumor Institute.

出版信息

Zhonghua Wai Ke Za Zhi. 1993 Feb;31(2):85-7.

PMID:8223012
Abstract

Liquid nitrogen (LN) cryosurgery is more often used for the treatment of bone tumors of the extremities. Since 1985 after animal experimentation we began to use it for the surgical treatment of spinal tumors. The temperature of the tissues surrounding the spinal cord was controlled above -20 degrees C by means of thermocouples and somatosensory evoked potentials (SEP) was used to monitor the spinal cord function. Liquid nitrogen was used as an adjuvant treatment in the surgical treatment of spinal tumors, it could reduce operative hemorrhage and kill tumor cells. The function of spinal cord had not been damaged in all 11 patients after cryotherapy. There was infection in one case, it was cured by using antibiotics and by drainage. This study showed that LN freezing can reduce the amount of operative hemorrhage during resection of spinal tumors. Benign tumors can be thus removed easily and thoroughly.

摘要

液氮冷冻手术更常用于治疗四肢骨肿瘤。自1985年经过动物实验后,我们开始将其用于脊柱肿瘤的手术治疗。通过热电偶将脊髓周围组织的温度控制在-20℃以上,并使用体感诱发电位(SEP)来监测脊髓功能。液氮被用作脊柱肿瘤手术治疗的辅助手段,它可以减少手术出血并杀死肿瘤细胞。11例患者冷冻治疗后脊髓功能均未受损。有1例发生感染,通过使用抗生素和引流治愈。本研究表明,液氮冷冻可减少脊柱肿瘤切除术中的手术出血量。良性肿瘤因此可以轻松、彻底地切除。

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