铝与阿尔茨海默病之间存在关联吗？
Is there any relationship between aluminum and Alzheimer's disease?
作者信息
Eichhorn G L
机构信息
National Institutes of Health, National Institute on Aging, Laboratory of Cellular and Molecular Biology, Baltimore, Maryland 21224.
出版信息
Exp Gerontol. 1993 Jul-Oct;28(4-5):493-8. doi: 10.1016/0531-5565(93)90074-n.
PMID:8224045
Abstract
The controversial role of aluminum in Alzheimer's disease (AD) is reviewed. While current data would suggest the lack of a causative role, alterations in the brain and other organ systems caused by AD might increase the penetration of aluminum as well as other metals into the brain and lead to their contribution to such pathological features as neurofibrillar tangles (NFTs).
摘要
本文综述了铝在阿尔茨海默病（AD）中存在争议的作用。虽然目前的数据表明铝缺乏致病作用，但AD导致的大脑和其他器官系统的改变可能会增加铝以及其他金属进入大脑的渗透率，并导致它们对神经原纤维缠结（NFTs）等病理特征产生影响。
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