Scully C
Department of Oral Medicine, Pathology and Microbiology, University of Bristol Dental Hospital and School, UK.
Dent Update. 1993 Apr;20(3):95-100.
Understanding the pathogenesis of cancer may well lead to improved diagnostic tests, preventive treatment and management. This paper reviews the gene changes, the evidence implicating viruses in the aetiology of oral cancer, and the mechanisms whereby viruses may affect gene function and thereby contribute to carcinogenesis.
了解癌症的发病机制很可能会带来改进的诊断测试、预防性治疗和管理方法。本文综述了基因变化、病毒在口腔癌病因学中作用的证据,以及病毒可能影响基因功能从而促进癌变的机制。