口腔鳞状细胞癌中的癌基因、肿瘤抑制基因与病毒
Oncogenes, tumor suppressors and viruses in oral squamous carcinoma.
作者信息
Scully C
机构信息
University Department of Oral Medicine, Pathology and Microbiology, Bristol Dental Hospital and School, England.
出版信息
J Oral Pathol Med. 1993 Sep;22(8):337-47. doi: 10.1111/j.1600-0714.1993.tb01086.x.
Abstract
The pathogenesis of oral squamous cell carcinoma involves recognised carcinogens in tobacco and/or alcohol but other factors, including viruses, may also have a role. This paper reviews the gene changes revealed in oral carcinoma, the evidence implicating viruses, and mechanisms whereby viruses may affect gene function.
摘要
口腔鳞状细胞癌的发病机制涉及烟草和/或酒精中公认的致癌物，但其他因素，包括病毒，也可能起作用。本文综述了口腔癌中发现的基因变化、涉及病毒的证据以及病毒可能影响基因功能的机制。
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