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猪持续回避行为中与恐惧相关的变化。I. 地西泮对辨别性恐惧条件反射表现的影响缺乏

Fear-dependent variations in continuous avoidance behavior of pigs. I. Lack of effect of diazepam on performance of discriminative fear conditioning.

作者信息

Dantzer R, Mormede P

出版信息

Psychopharmacology (Berl). 1976 Aug 26;49(1):69-73. doi: 10.1007/BF00427473.

Abstract

Pigs trained to avoid shocks by crossing a barrier in a shuttle-box according to a continuous avoidance procedure were submitted to a Pavlovian discriminative fear-conditioning procedure in which a tone was always followed by unavoidable shock (CS+) and another tone never followed by shock (CS-). The presentation of the CS+ on a test session in the shuttle-box induced an increase of the response rate while the CS- decreased the performance. Diazepam (1 mg/kg) administered before the test session did not modify the changes in avoidance response to each CS.

摘要

通过穿梭箱中的连续回避程序训练猪,使其学会越过障碍物以避免电击,然后对这些猪进行巴甫洛夫鉴别性恐惧条件反射程序,在此程序中,一种音调总是紧接着不可避免的电击(条件刺激+,CS+),而另一种音调从不伴随电击(条件刺激-,CS-)。在穿梭箱测试阶段呈现CS+会导致反应率增加,而CS-则会降低表现。在测试阶段前给予地西泮(1毫克/千克)并没有改变对每种CS的回避反应变化。

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