Gogvadze V, Zhukova A
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino.
Gen Physiol Biophys. 1993 Jun;12(3):303-8.
Addition of thenoyltrifluoracetone to mitochondria oxidizing NAD-dependent substrates induced lipid peroxidation and uncoupling of oxidative phosphorylation. Butylated hydroxytoluene, an antioxidant, prevented accumulation of lipid peroxidation products but failed to prevent deenergization of the mitochondria.
将噻吩甲酰三氟丙酮添加到氧化依赖于NAD的底物的线粒体中，会诱导脂质过氧化和氧化磷酸化解偶联。抗氧化剂丁基羟基甲苯可防止脂质过氧化产物的积累，但未能阻止线粒体的能量耗散。
