[Participation of phospholipase A2 in uncoupling in rat liver mitochondria induced by products of lipid peroxidation].
作者信息
Gogvadze V G, Bruetovetskiĭ N N, Zhukova A A
出版信息
Biokhimiia. 1990 Dec;55(12):2195-9.
PMID:2129018
Abstract
Accumulation of lipid peroxidation products induced by cumol hydroperoxide (230 microM) results in the loss of the membrane potential only in calcium-loaded mitochondria. The phospholipase A2 inhibitor, p-bromophenylacylbromide, prevents mitochondrial uncoupling but has no effect on the accumulation of lipid peroxidation products.
摘要
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