Arnon R, Fich A, Bar-Ziv J
Gastroenterology Unit, Hadassah-University Hospital, Jerusalem.
Harefuah. 1993 Aug;125(3-4):86-9, 127.
Achalasia is usually a primary disorder of esophageal motility, but has been described in association with other pathological processes, such as malignancy. A 79-year-old man with achalasia secondary to gastric adenocarcinoma is presented. The differential diagnosis of secondary achalasia includes infectious and infiltrative disease and neuropathy, but mainly malignant diseases. The clinical criteria found for achalasia secondary to malignancy included older age at diagnosis, brief duration of symptoms, and weight loss. While upper gastrointestinal x-rays and computerized tomographic scanning may be helpful, the most reliable diagnostic tool is esophago-gastro-duodenoscopy. This is a terminal disease with short life expectancy. Yet making the correct diagnosis can save the patient from futile treatment with muscle relaxants and endoscopic balloon dilatation, the accepted therapeutic measures in primary achalasia.
贲门失弛缓症通常是一种原发性食管动力障碍性疾病,但也有与其他病理过程相关的报道,如恶性肿瘤。本文报告了一名79岁继发于胃腺癌的贲门失弛缓症男性患者。继发性贲门失弛缓症的鉴别诊断包括感染性和浸润性疾病以及神经病变,但主要是恶性疾病。继发于恶性肿瘤的贲门失弛缓症的临床标准包括诊断时年龄较大、症状持续时间短和体重减轻。虽然上消化道X线检查和计算机断层扫描可能有所帮助,但最可靠的诊断工具是食管胃十二指肠镜检查。这是一种预期寿命较短的终末期疾病。然而,做出正确的诊断可以使患者避免接受原发性贲门失弛缓症公认的治疗措施——使用肌肉松弛剂和内镜球囊扩张进行徒劳的治疗。