McCallum R W
Am J Gastroenterol. 1979 Jan;71(1):24-9.
A case of invasive gastric carcinoma mimicking idiopathic achalasia radiologically, endoscopically and manometrically is described. This is only the second case of tumor-associated achalasia with a positive mecholyl test where there was no demonstrable histological tumor involvement of the myenteric plexus in the body of the esophagus. The interpretation of the manometric findings including the positive mecholyl test are discussed in the light of these histological findings. The short duration of symptoms, the presence of anemia and guaiac positive stools, along with subtle radiologic abnormalities of the gastric fundus were aspects of this case which should increase the index of suspicion and lead to the correct diagnosis. In the evaluation of patients with the achalasic syndrome, a tumor-associated functional and organic disorder mimicking idiopathic achalasia in all respects has to be considered.
本文描述了一例在放射学、内镜检查和测压方面均酷似特发性贲门失弛缓症的浸润性胃癌病例。这是第二例肿瘤相关性贲门失弛缓症且乙酰甲胆碱试验呈阳性的病例,该病例中食管体部的肌间神经丛未发现明显的组织学肿瘤浸润。结合这些组织学发现,对包括乙酰甲胆碱试验阳性在内的测压结果进行了解读。症状持续时间短、存在贫血和粪便潜血阳性,以及胃底细微的放射学异常,是该病例的一些特征,这些特征应提高怀疑指数并有助于做出正确诊断。在评估贲门失弛缓综合征患者时,必须考虑一种在各方面都酷似特发性贲门失弛缓症的肿瘤相关性功能和器质性疾病。