Berlinsky S, Serov B, Shiber A
Psychiatric Dept. Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheba.
Harefuah. 1993 Sep;125(5-6):138-41, 192, 191.
It has been observed clinically that the mean corpuscular volume (MCV) of erythrocytes is increased in psychiatric patients, but this phenomenon has not been investigated. We therefore compared the MCV of 177 patients in our psychiatric day care ward and in our psychiatric outpatient clinic. The MCV of these psychiatric patients, and especially that of the outpatients, were significantly greater than that of normal controls. No association was found between MCV and sociodemographic or clinical variables. The sensitivity of a high MCV level as a diagnostic for folic acid deficiency was 42.9%, with a specificity of 80.6%. The sensitivity of a high MCV level as a diagnostic for vitamin B12 deficiency was 23.1%, with a specificity of 79.4%.
临床上观察到，精神病患者红细胞的平均体积（MCV）增加，但这一现象尚未得到研究。因此，我们比较了精神科日间护理病房和精神科门诊的177名患者的MCV。这些精神病患者的MCV，尤其是门诊患者的MCV，显著高于正常对照组。未发现MCV与社会人口统计学或临床变量之间存在关联。MCV水平升高作为叶酸缺乏诊断指标的敏感性为42.9%，特异性为80.6%。MCV水平升高作为维生素B12缺乏诊断指标的敏感性为23.1%，特异性为79.4%。
