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[与脑出血相比,各种脑梗死组的急性预后及鉴别]

[Acute prognosis and differentiation of various cerebral infarct groups in comparison with cerebral hemorrhage].

作者信息

Weitbrecht W U

机构信息

Neurologische Klinik, KKH Gummersbach.

出版信息

Fortschr Neurol Psychiatr. 1993 Sep;61(9):301-9. doi: 10.1055/s-2007-999098.

DOI:10.1055/s-2007-999098
PMID:8225151
Abstract

For clinical trials classification of stroke should be possible at the bedside by simple methods that are available every where. In this study are 1105 patients with every first ischaemic strokes and 130 patients with intracerebral haemorrhages. The differences between severity of clinical symptoms, outcome and risk factors of intracerebral haemorrhages, ischaemic stroke caused by cerebral microangiopathy, ischaemic stroke combined with extracranial carotid stenosis, cardiogenic brain embolism and atherothrombotic stroke, were analysed. Intracerebral haemorrhages show the poorest outcome of all groups (mortality 23.8%), due to increased intracranial pressure. Cardiogenic brain embolism is more frequent in older women (mean age 77.8 y.). Main risk factor is atrial fibrillation with absolute arrhythmia. The outcome of this group is the worst of all subgroups of ischaemic stroke and survivors most often in need of institutionalization. Patients with ischaemic stroke combined with extracranial carotid stenosis are significantly younger (mean age 67.6 y.), predominantly male, and smokers. Their mortality is low (0.63%), but recovery of paresis is slower than in other subgroups. Ischaemic strokes caused by cerebral microangiopathy with hypertension as main risk factor recover most quickly but acute mortality is higher than in ischaemic stroke combined with extracranial carotid stenosis because of higher age (mean age 74.5 y.). Institutionalization is more frequent too because of higher incidence of dementia in this subgroup. The main prognostic factors of all groups are age and severity of clinical symptoms. A special subgroup are infratentorial ischaemic strokes.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对于临床试验而言,应能够通过各地都具备的简单方法在床边对中风进行分类。本研究纳入了1105例首次发生缺血性中风的患者以及130例脑出血患者。分析了脑出血、脑微血管病变所致缺血性中风、合并颅外颈动脉狭窄的缺血性中风、心源性脑栓塞和动脉粥样硬化血栓形成性中风在临床症状严重程度、预后及危险因素方面的差异。脑出血在所有组中预后最差(死亡率23.8%),原因是颅内压升高。心源性脑栓塞在老年女性中更为常见(平均年龄77.8岁)。主要危险因素是伴有绝对心律失常的心房颤动。该组的预后是缺血性中风所有亚组中最差的,幸存者最常需要入住机构护理。合并颅外颈动脉狭窄的缺血性中风患者明显更年轻(平均年龄67.6岁),以男性为主,且多为吸烟者。他们的死亡率较低(0.63%),但瘫痪恢复比其他亚组慢。以高血压为主要危险因素的脑微血管病变所致缺血性中风恢复最快,但由于年龄较大(平均年龄74.5岁),急性死亡率高于合并颅外颈动脉狭窄的缺血性中风。由于该亚组痴呆发病率较高,入住机构护理的情况也更常见。所有组的主要预后因素是年龄和临床症状的严重程度。幕下缺血性中风是一个特殊的亚组。(摘要截选至250词)

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