Vora S U, Karnad P D, Kshirsagar N A, Kamat S R
Department of Pharmacology, Seth G.S. Medical College, Parel, Bombay.
Indian J Chest Dis Allied Sci. 1993 Jan-Mar;35(1):31-4.
Increased mucociliary activity has been observed with several modalities, including inhalation which seems to achieve faster drug delivery. In patients of chronic lung disease, the mucociliary activity is known to be impaired. The effect of steam inhalation on mucociliary transport time was studied in these patients. It was found that steam inhalation improved mucociliary activity significantly (p < 0.001) in both groups receiving either only bronchodilators, or bronchodilators as well as steroids.
通过多种方式已观察到黏液纤毛活性增加，包括吸入，吸入似乎能实现更快的药物递送。在慢性肺病患者中，已知黏液纤毛活性受损。对这些患者进行了蒸汽吸入对黏液纤毛转运时间影响的研究。结果发现，在仅接受支气管扩张剂或同时接受支气管扩张剂和类固醇的两组患者中，蒸汽吸入均显著改善了黏液纤毛活性（p < 0.001）。
