Viel J F
Department of Public Health, Faculty of Medicine, Besançon, France.
Int J Epidemiol. 1993 Aug;22(4):627-31. doi: 10.1093/ije/22.4.627.
Positive associations between leukaemia and radon concentrations have been observed in England, Scotland and Wales, and Canada. Results of a similar study for the populations of 41 French administrative areas ('départements') are reported for 1984-1986. The average indoor radon and gamma ray concentrations per 'département' range from 12 to 147 Bq.m-3 and from 28 to 142 nG.h-1, respectively. Acute lymphoid leukaemia mortality rate is similar to the national level, whereas an excess of acute myeloid leukaemia deaths is observed. According to Poisson regression models and modified tests for partial correlation, acute myeloid leukaemia mortality is significantly and positively related to indoor radon concentration whether or not adjustment is made for indoor gamma ray dose, socioeconomic status and linear gradient. This result reinforces the evidence that indoor exposure to high levels of radon is a leukaemic environmental hazard.
在英格兰、苏格兰、威尔士以及加拿大，人们观察到白血病与氡浓度之间存在正相关关系。本文报告了1984 - 1986年针对法国41个行政区（“省”）人口进行的一项类似研究的结果。每个“省”的室内氡平均浓度和伽马射线浓度分别在12至147贝克勒尔·立方米⁻³和28至142纳戈瑞·小时⁻¹之间。急性淋巴细胞白血病死亡率与全国水平相近，然而观察到急性髓细胞白血病死亡人数有所增加。根据泊松回归模型和偏相关的修正检验，无论是否对室内伽马射线剂量、社会经济地位和线性梯度进行调整，急性髓细胞白血病死亡率都与室内氡浓度显著正相关。这一结果进一步证明室内接触高浓度氡是白血病的一种环境危害。
