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[消化性溃疡出血的手术治疗:短期和长期结果]

[Surgery for bleeding peptic ulcer: short- and long-term results].

作者信息

Mueller X, Rothenbühler J M, Meyer B, Beglinger C

机构信息

Clinique de chirurgie générale, Hôpital cantonal universitaire de Bâle.

出版信息

Helv Chir Acta. 1993 Sep;60(1-2):101-4.

PMID:8226034
Abstract

Thirty-one patients operated on for bleeding peptic ulcer were reviewed. The basic concept was to make an early decision to operate and proceed as soon as the patient was haemodynamically stable. In addition to haemostasis, a definitive operation was performed. The procedure was a proximal gastric vagotomy (PGV) for duodenal ulcers (DU), combined with an antrectomy for pre-pyloric ulcers, and either a PGV with ulcer excision or a Billroth I for gastric (GU) or combined (GU + DU) ulcers. Twenty-four patients (77%) were operated on within the first 24 hours. Nine patients could not be operated according to the basic protocol because of anatomical reason, additional ulcer complication or severe co-existing systemic disease. During the hospital stay, 2 deaths (6%) occurred and 4 patients (13%) rebled postoperatively, all of them were reoperated. During a mean follow-up of 44 months, 12 deaths unrelated to peptic disease and one recurrent bleeding occurred. PGV for DU could be used in 70% of cases without any hospital mortality; one patient rebled after the operation and another during the long-term follow-up. These results support the views that early surgery has a low hospital mortality and that PGV gives good results when performed as an emergency procedure.

摘要

对31例因消化性溃疡出血而接受手术的患者进行了回顾性研究。基本理念是尽早做出手术决定,并在患者血流动力学稳定后尽快进行手术。除了止血外,还进行了确定性手术。对于十二指肠溃疡(DU),手术方式为近端胃迷走神经切断术(PGV);对于幽门前溃疡,手术方式为PGV联合胃窦切除术;对于胃溃疡(GU)或复合性溃疡(GU + DU),手术方式为PGV联合溃疡切除术或毕罗一式手术。24例患者(77%)在最初24小时内接受了手术。9例患者因解剖原因、额外的溃疡并发症或严重的并存全身性疾病,未能按照基本方案进行手术。住院期间,发生2例死亡(6%),4例患者(13%)术后再次出血,均再次接受了手术。在平均44个月的随访期间,发生了12例与消化性疾病无关的死亡和1例复发性出血。70%的DU患者可采用PGV手术,无医院死亡病例;1例患者术后再次出血,另1例在长期随访期间再次出血。这些结果支持以下观点:早期手术的医院死亡率较低,且PGV作为急诊手术效果良好。

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