Walsh T J
Pediatric Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Hematol Oncol Clin North Am. 1993 Oct;7(5):1003-26.
Invasive fungal infections have emerged as major causes of morbidity and mortality in immunocompromised patients, particularly granulocytopenic and HIV-infected hosts. Diagnosis and treatment of these infections is determined by the type of fungus and the sites of infection. While Candida spp. and Aspergillus spp. are the most common causes of fungal infection in granulocytopenic patients, less common pathogens are emerging as new challenges. This article summarizes current approaches used in the National Cancer Institute's Pediatric Branch for management of invasive fungal infections.
侵袭性真菌感染已成为免疫功能低下患者发病和死亡的主要原因，尤其是粒细胞减少和感染HIV的宿主。这些感染的诊断和治疗取决于真菌的类型和感染部位。虽然念珠菌属和曲霉属是粒细胞减少患者真菌感染的最常见原因，但不太常见的病原体正成为新的挑战。本文总结了美国国立癌症研究所儿科分部用于管理侵袭性真菌感染的当前方法。
