霍奇金病患者外周血中B淋巴细胞和T淋巴细胞的分布
The distribution of B and T lymphocytes in the peripheral blood of patients with Hodgkin's disease.
作者信息
Many A, Biniaminov M, Rosenthal E, Aghai E, Ramot B
出版信息
Acta Haematol. 1976;56(1):1-6. doi: 10.1159/000207911.
PMID:822670
Abstract
The distribution of thymus-dependent (T cells) and bone marrow-derived lymphocytes (B cells) was studied in 74 patients with Hodgkin's disease and 33 normal controls. A T cell deficit was found in untreated patients as well as in long-term survivors in remission. Therapy slightly enhanced the T cell depletion in Hodgkin's disease patients. Concomitant with this finding was slight increase of B cells.
摘要
对74例霍奇金病患者和33名正常对照者的胸腺依赖性淋巴细胞（T细胞）和骨髓来源淋巴细胞（B细胞）分布情况进行了研究。在未经治疗的患者以及处于缓解期的长期存活者中均发现存在T细胞缺陷。治疗略微加重了霍奇金病患者的T细胞耗竭。与此发现相伴的是B细胞略有增加。
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