Shinya K, Uchida K, Nomura K, Ozaki K, Narama I, Umemura T
Department of Veterinary Pathology, Faculty of Agriculture, Tottori University, Japan.
J Vet Med Sci. 1997 Oct;59(10):949-50. doi: 10.1292/jvms.59.949.
A mass of glomus tumor was found on the skin of the right foreleg of a ten-year old male mongrel dog. Histologically the mass contained some vasculatures and sheet-like proliferation of epithelioid tumor cells. Some blood vessels were rimmed by the tumor cells, which had a round to ovoid nucleus and plump eosinophilic cytoplasm. Immunohistochemically, smooth muscle actin and vimentin were demonstrated in the tumor cells. By electron microscopic examination, actin-like filaments with dense bodies were observed in the cytoplasm of the tumor cells. This is the first case report of a canine glomus tumor.
在一只10岁雄性杂种犬的右前肢皮肤上发现了一团血管球瘤。组织学上，该肿物含有一些血管以及上皮样肿瘤细胞的片状增生。一些血管被肿瘤细胞包绕，肿瘤细胞具有圆形至卵圆形细胞核和丰满的嗜酸性细胞质。免疫组织化学检查显示，肿瘤细胞中存在平滑肌肌动蛋白和波形蛋白。通过电子显微镜检查，在肿瘤细胞的细胞质中观察到带有致密小体的肌动蛋白样细丝。这是犬血管球瘤的首例病例报告。
