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[枯草芽孢杆菌中分解代谢物阻遏与芽孢形成之间的关系(作者译)]

[Relations between catabolite repression and sporulation in Bacillus subtilis (author's transl)].

作者信息

López J M, Thoms B

出版信息

Arch Microbiol. 1976 Aug;109(1-2):181-6. doi: 10.1007/BF00425133.

Abstract

Acetoin dehydrogenase can be catabolite repressed by numerous sources of carbon. The following results point out that the catabolite repression of this enzyme and the inhibition of sporulation are mediated by the same mechanism: 1. Mutants, able to synthesize acetoin dehydrogenase in the presence of glucose, sporulate in glucose medium at a higher rate than the standard strain. 2. The catabolite repressing effect of a compound and its ability to inhibit sporulation are in a direct relation to each other. 3. The limitation of inorganic phosphate in the growth medium, which is known to favour sporulation, counteracts the catabolite repressing effect of glucose.

摘要

乙偶姻脱氢酶可被多种碳源进行分解代谢物阻遏。以下结果表明,该酶的分解代谢物阻遏作用和孢子形成的抑制作用是由相同机制介导的:1. 能够在葡萄糖存在下合成乙偶姻脱氢酶的突变体,在葡萄糖培养基中的孢子形成速率高于标准菌株。2. 一种化合物的分解代谢物阻遏作用及其抑制孢子形成的能力彼此直接相关。3. 已知有利于孢子形成的生长培养基中无机磷酸盐的限制,可抵消葡萄糖的分解代谢物阻遏作用。

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