Margotta V, Filoni S, Del Vecchio P
Dipartimento di Biologia animale e dell'Uomo (Facoltà di Scienze), Università di Roma La Sapienza, Italy.
J Hirnforsch. 1993;34(2):231-8.
Brains of adult Urodele Amphibians (Triturus carnifex Laur.) were homoplastically transplanted in conditions of complete morpho-functional isolation and fixed 100 and 365 days after the operation. Results show that in the post-telencephalic regions structural organization disappear in all cases, while, in some cases the telencephalon retain a fairly complex structural organization even after one year. The heterogeneous nature of the histological patterns observed may be attributed to the different size of the matrix areas, besides the different degree of immune response of the host to the graft. In the telencephalic district, where the matrix areas are particularly well developed, undifferentiated elements of these areas would be capable of opposing the degenerative phenomena in the transplants by neoformation of neurons. However, in post-telencephalic districts, where the matrix areas are less developed or absent, it would not be possible to make up for neuronal degeneration and these regions disappear or are formed only by some undifferentiated elements outside the surviving ependyma portions.
将成年有尾两栖动物（Triturus carnifex Laur.）的大脑在完全形态功能隔离的条件下进行同种异体移植，并在术后100天和365天进行固定。结果表明，在所有情况下，终脑后部区域的结构组织均消失，而在某些情况下，即使在一年后，终脑仍保留相当复杂的结构组织。除了宿主对移植物的免疫反应程度不同外，观察到的组织学模式的异质性可能归因于基质区域的大小不同。在终脑区域，基质区域特别发达，这些区域的未分化成分能够通过神经元的新形成来对抗移植物中的退化现象。然而，在终脑后部区域，基质区域发育较差或不存在，无法弥补神经元的退化，这些区域消失或仅由存活的室管膜部分之外的一些未分化成分形成。
