Martinez-Lopez J I, Cortés E
Texas Tech University Health Sciences Center, Dept of Medicine, in El Paso.
J La State Med Soc. 1993 Jul;145(7):317-20.
The electrophysiologic responses to intravenous adenosine observed in a patient with automatic atrial tachycardia are presented. Although the development of advanced AV block was not unexpected, prolongation of atrial cycle lengths before the abrupt termination of the arrhythmia, and the subsequent transient, but total, suppression of all electrical cardiac activity were. The atrial arrhythmia reappeared when adenosine effects dissipated. The current tendency to use intravenous adenosine as the drug of first choice in the acute management and diagnosis of paroxysmal supraventricular arrhythmias, despite its lack of superiority over verapamil, will probably result in many more reports of unexpected adverse effects following its use.
本文报道了一名自动性房性心动过速患者静脉注射腺苷后的电生理反应。虽然出现高度房室传导阻滞并不意外，但心律失常突然终止前心房周期长度的延长以及随后所有心脏电活动的短暂但完全抑制却出乎意料。当腺苷作用消失时，房性心律失常再次出现。尽管静脉注射腺苷在阵发性室上性心律失常的急性处理和诊断中并不比维拉帕米更具优势，但目前将其作为首选药物的趋势可能会导致更多关于其使用后意外不良反应的报道。
