Lawrence V A, Gafni A, Kroenke K
Department of Medicine, University of Texas Health Science Center at San Antonio 78284-7879.
J Clin Epidemiol. 1993 Nov;46(11):1219-27. doi: 10.1016/0895-4356(93)90084-e.
Universal precautions are officially recommended to prevent HIV transmission in health care settings but for elective surgery some advocate routine preoperative HIV testing. These strategies have not been tested in clinical trials but universal precautions are very expensive and not cost-effective. Thus, for elective surgery, routine testing might save resources by permitting selective use of additional barrier precautions. We performed an economic evaluation to compare both strategies, using a simple approach to determine if routine testing (RT) is less expensive than universal precautions (UP). Conservatively assuming equal effectiveness in preventing HIV transmission, we compared a minimized estimate for the average cost of RT with a maximized estimate for the average cost of UP per elective operation. The minimized estimate for RT (US$57) was greater than the maximized estimate for UP (US$36) per procedure. Results were stable or strengthened by sensitivity analysis. Routine HIV testing is not a valid economic alternative to UP for elective surgery. The simple methodology used in this study can be a preliminary strategy to review other strategies for preventing HIV transmission. This method is particularly useful when data are inadequate for a formal economic evaluation to determine the utility of collecting the detailed information necessary for a full comparison.
官方建议采取普遍预防措施以防止医疗环境中的艾滋病毒传播,但对于择期手术,一些人主张进行术前常规艾滋病毒检测。这些策略尚未在临床试验中得到检验,而且普遍预防措施成本高昂且不具成本效益。因此,对于择期手术,常规检测可能通过允许有选择地使用额外的屏障预防措施来节省资源。我们进行了一项经济评估以比较这两种策略,采用一种简单方法来确定常规检测(RT)是否比普遍预防措施(UP)成本更低。保守地假设在预防艾滋病毒传播方面效果相同,我们将RT平均成本的最低估计值与每次择期手术UP平均成本的最高估计值进行了比较。每次手术RT的最低估计值(57美元)高于UP的最高估计值(36美元)。敏感性分析使结果保持稳定或得到强化。对于择期手术,常规艾滋病毒检测并非UP有效的经济替代方案。本研究中使用的简单方法可以作为审查其他预防艾滋病毒传播策略的初步策略。当数据不足以进行正式的经济评估以确定收集全面比较所需详细信息的效用时,这种方法特别有用。