Miyazaki T
Department of Otolaryngology, Asanogawa General Hospital, Kanazawa.
Nihon Jibiinkoka Gakkai Kaiho. 1993 Sep;96(9):1471-81. doi: 10.3950/jibiinkoka.96.1471.
Detection of calcification of the thyroid gland is very useful for the clinical diagnosis and therapy of thyroid cancer. In this study, we evaluated the usefulness of FCR (Fuji computed radiography) and CT by analyzing the correlation between the imaging findings of calcification and histological diagnosis. Fifty-one cases of follicular adenoma and 63 cases of differentiated carcinoma underwent FCR and CT. All cases undergoing operation received histological examination. Calcification was detected in 19.6% of follicular adenomas and in 46.0% of differentiated carcinomas by FCR, and 37.3% of follicular adenomas and in 63.5% of differentiated carcinomas by CT. Among cases without calcification on FCR, CT detected calcification in 26.7%. These differences between the results of FCR and CT were found in cases with small calcifications, low thyroid gland position and in whom differentiation between tracheal cartilage calcification and thyroid carcinoma calcification was difficult. In these cases, calcification was difficult to detect by FCR alone. Patients with follicular adenoma aged > or = 60 years showed a higher prevalence of calcification than younger patients. In cases of differentiated carcinoma, no relationship was seen between age and the prevalence of calcification. The classification of calcification shape by FCR showed that the majority of psammoma bodies, as well as sharp and irregular shapes, were found in differentiated carcinoma while round calcifications were found in follicular adenomas. On CT, calcification inside the tumor was found in 73.7% of follicular adenomas and in 92.5% of differentiated carcinomas. FCR and CT are more useful for the detection of calcification than conventional radiography and are of great value in screening for thyroid tumors.
甲状腺钙化的检测对甲状腺癌的临床诊断和治疗非常有用。在本研究中，我们通过分析钙化的影像学表现与组织学诊断之间的相关性，评估了富士计算机X线摄影（FCR）和CT的作用。51例滤泡性腺瘤和63例分化型癌患者接受了FCR和CT检查。所有接受手术的病例均进行了组织学检查。FCR检测到19.6%的滤泡性腺瘤和46.0%的分化型癌有钙化，CT检测到37.3%的滤泡性腺瘤和63.5%的分化型癌有钙化。在FCR检查无钙化的病例中，CT检测到钙化的比例为26.7%。FCR和CT结果的这些差异见于钙化较小、甲状腺位置较低以及气管软骨钙化与甲状腺癌钙化难以鉴别的病例。在这些病例中，仅靠FCR很难检测到钙化。年龄≥60岁的滤泡性腺瘤患者钙化发生率高于年轻患者。在分化型癌病例中，年龄与钙化发生率之间未见相关性。FCR对钙化形态的分类显示，砂粒体以及尖锐和不规则形态的钙化多见于分化型癌，而圆形钙化见于滤泡性腺瘤。CT检查发现，73.7%的滤泡性腺瘤和92.5%的分化型癌肿瘤内部有钙化。FCR和CT在检测钙化方面比传统X线摄影更有用，对甲状腺肿瘤的筛查具有重要价值。
