Schweiger H, Klein P, Lang W
Department of Vascular Surgery, University of Erlangen-Nürnberg, Germany.
J Vasc Surg. 1993 Nov;18(5):867-74.
In advanced peripheral ischemia, tibial artery prosthetic bypass grafting is virtually the last chance for limb salvage when conservative treatment and other methods of revascularization have failed.
For this study we reviewed our 7 years of experience with below-popliteal artery polytetrafluoroethylene grafts implanted for limb salvage.
All results regarding graft patency and limb salvage were computed by actuarial methods and were presented in the form of life-table analysis. There were 211 grafts in 184 patients (195 limbs). Two and 5 years after the operation, primary patency rates were 37% and 23% and secondary patency rates were 45% and 25%, respectively. The main negative predictive factors for patency rate were an occluded primary plantar arch artery and poor vessel runoff. Primary bypass procedures had markedly better success rates than secondary (repeat) procedures, with primary patency rates of 52% at 2 years and 42% at 4 years, whereas the corresponding rates for secondary procedures were 22% and 14%, respectively. The 5-year cumulative limb salvage rate was 51% for the total series.
Although the patency of prosthetic grafts is not as satisfactory as that of autologous vein grafts, the limb salvage rate justifies an aggressive approach to infrapopliteal bypass grafting with polytetrafluoroethylene prostheses when the limb is threatened and vein is not available.
在晚期外周缺血中,当保守治疗和其他血管重建方法失败时,胫动脉人工血管搭桥术实际上是挽救肢体的最后机会。
在本研究中,我们回顾了7年来为挽救肢体而植入腘动脉以下聚四氟乙烯移植物的经验。
所有关于移植物通畅率和肢体挽救率的结果均采用精算方法计算,并以生命表分析的形式呈现。184例患者(195条肢体)共植入211条移植物。术后2年和5年,一期通畅率分别为37%和23%,二期通畅率分别为45%和25%。通畅率的主要负性预测因素是足底弓动脉闭塞和血管流出道不佳。一期搭桥手术的成功率明显高于二期(重复)手术,2年一期通畅率为52%,4年为42%,而二期手术相应的通畅率分别为22%和14%。整个系列的5年累积肢体挽救率为51%。
尽管人工血管移植物的通畅率不如自体静脉移植物,但当肢体受到威胁且无法获得静脉时,肢体挽救率证明在腘动脉以下使用聚四氟乙烯人工血管进行搭桥手术时应采取积极的方法。