Fujita S, Teramoto T, Watanabe M, Kodaira S, Kitajima M
Department of Surgery, School of Medicine, Keio University, Tokyo.
Jpn J Clin Oncol. 1993 Oct;23(5):299-302.
In order to discover the incidence of recurrence and prognosis of patients with anastomotic leakage after colorectal surgery, 980 colorectal cancer patients who underwent anastomosis at Keio University Hospital between 1970 and 1990 were examined. Thirty-three patients (leakage group) out of the 980 exhibited anastomotic leakage. The incidence of local recurrence in the leakage group was significantly higher than in the no leakage group (P < 0.01). The disease-free survival rate of the leakage group was significantly lower than that of the no leakage group in Dukes' A, B patients (P < 0.01), but was not so in Dukes' C, D patients. These results suggested that anastomotic leakage after colorectal cancer surgery might enhance the incidence of local recurrence and make the prognosis poor.
为了探究结直肠手术后吻合口漏患者的复发率及预后情况，对1970年至1990年间在庆应义塾大学医院接受吻合术的980例结直肠癌患者进行了检查。980例患者中有33例（漏组）出现吻合口漏。漏组的局部复发率显著高于无漏组（P < 0.01）。在Dukes' A、B期患者中，漏组的无病生存率显著低于无漏组（P < 0.01），但在Dukes' C、D期患者中并非如此。这些结果表明，结直肠癌手术后的吻合口漏可能会增加局部复发率并使预后变差。
