Itasaka Y, Miyazaki S, Tada H, Ishikawa K, Togawa K
Department of Otolaryngology, Akita University School of Medicine, Japan.
Psychiatry Clin Neurosci. 1998 Apr;52(2):225-7. doi: 10.1111/j.1440-1819.1998.tb01044.x.
Fifteen patients with obstructive sleep apnea were treated using prosthetic mandibular advancement (PMA). Each patient was evaluated in the supine and lateral decubitus positions with and without PMA. After PMA treatment, the mean intraesophageal pressure (Peso) in the supine position improved from -42.6 to -27.3 cmH2O and the mean apnea + hypopnea index (AHI) decreased from 48.8/h to 23.7/h. The mean Peso in the lateral decubitus position improved from -27.9 to -18.6 cmH2O and the mean AHI decreased from 9.6/h to 6.6/h. With PMA, respiratory, disturbance during sleep further improved by changing the body position from the supine to lateral decubitus position.
15名阻塞性睡眠呼吸暂停患者接受了下颌前移修复术（PMA）治疗。对每位患者在仰卧位和侧卧位分别进行了有无PMA的评估。PMA治疗后，仰卧位时平均食管内压（Peso）从-42.6 cmH₂O改善至-27.3 cmH₂O，平均呼吸暂停+低通气指数（AHI）从48.8次/小时降至23.7次/小时。侧卧位时平均Peso从-27.9 cmH₂O改善至-18.6 cmH₂O，平均AHI从9.6次/小时降至6.6次/小时。使用PMA时，通过将体位从仰卧位改为侧卧位，睡眠期间的呼吸紊乱进一步改善。
