Umebayashi Y, Yuda T, Fukuda S, Moriyama Y, Iguro Y, Saigenji H, Shimokawa S, Toyohira H, Taira A, Arikawa K
Second Department of Surgery, Kagoshima University, Faculty of Medicine, Japan.
Kyobu Geka. 1993 Nov;46(12):1013-6.
Twenty-two patients (mean age of 12.9 years) with ventricular septal defect (VSD) associated with aortic regurgitation (AR) were treated surgically. Sixteen patients had subpulmonic VSD and six had infracristal VSD. Fourteen patients with subpulmonic VSD underwent VSD closure alone. VSD was closed by pulling up the inferior rim to the pulmonary valve thus support the prolapse aortic cusp. AR improved in two and has remained stable in eleven for 0.5 to 12.7 years (mean 4.4 years). Aortic valve replacement (AVR) was necessary in an adult patient later. Plication of the aortic valve was effective in a young patient but ineffective in an adult patient. In infracristal VSD, AVR was necessary in two adult patients. In a young patient, AR improved by plication. Direct VSD closure ceased progression of AR in three patients. The long-term follow-up shows that VSD closure with our technique has been sufficient to arrest progression of AR in subpulmonic VSD. Early closure of VSD should be emphasized to prevent aortic valve prolapse and regurgitation.
22例室间隔缺损(VSD)合并主动脉瓣反流(AR)的患者接受了手术治疗。平均年龄12.9岁。16例为肺动脉瓣下室间隔缺损,6例为嵴下室间隔缺损。14例肺动脉瓣下室间隔缺损患者仅行室间隔缺损修补术。通过将下缘向上提拉至肺动脉瓣来关闭室间隔缺损,从而支撑脱垂的主动脉瓣叶。2例患者主动脉瓣反流改善,11例患者主动脉瓣反流在0.5至12.7年(平均4.4年)保持稳定。1例成年患者后来需要进行主动脉瓣置换术(AVR)。主动脉瓣折叠术对1例年轻患者有效,但对1例成年患者无效。在嵴下室间隔缺损患者中,2例成年患者需要进行主动脉瓣置换术。1例年轻患者通过主动脉瓣折叠术主动脉瓣反流改善。直接关闭室间隔缺损使3例患者的主动脉瓣反流停止进展。长期随访表明,采用我们的技术关闭室间隔缺损足以阻止肺动脉瓣下室间隔缺损患者主动脉瓣反流的进展。应强调早期关闭室间隔缺损以预防主动脉瓣脱垂和反流。