Gombos F, Serpico R, Femiano F, Zabatta A, Chiacchio R
Clinica Odontoiatrica e Stomatologica, Facoltà di Medicina e Chirurgia, Seconda Università degli Studi di Napoli.
Minerva Stomatol. 1993 Jun;42(6):257-64.
The increased prevalence of all variants of oral lichen, both as a result of increasing frequency and improved knowledge of the pathologist, coupled with its greater trend to malignant transformation has focused the attention of researchers on the development of new technology that could help in the early detection of the precancerous lesion. DNA cytometric detection can be useful to detect the precancerous lesion when clinical and histological findings of the transformation are still absent. The early diagnosis of such lesions entitles to use a more aggressive treatment, both medical and surgical.
口腔扁平苔藓所有变体的患病率增加，这既是由于发病率上升，也是因为病理学家的认知水平提高，再加上其恶变趋势增强，这使得研究人员将注意力集中在能够帮助早期检测癌前病变的新技术开发上。当仍缺乏病变转化的临床和组织学表现时，DNA细胞计量检测有助于检测癌前病变。对这类病变的早期诊断有利于采用更积极的治疗方法，包括药物治疗和手术治疗。
