Monticelli M L, Beghi E
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Neuroepidemiology. 1993;12(2):96-105. doi: 10.1159/000110307.
There are no data on the prevalence and other epidemiologic characteristics of chronic symmetric polyneuropathy (CSP) in the community. This study was designed to assess the prevalence and risk factors of CSP in well-defined elderly (55 years and older) populations from two separate areas in Italy. Thirty-five general practitioners working in the two areas were invited to interview a random sample of patients requesting consultation. They used a pretested questionnaire which focused on selected symptoms of polyneuropathy, common risk factors for CSP, and current drug treatments. Patients giving affirmative answers to the questions on screening symptoms received a further clinical evaluation by a neurologist. Details are given of the general characteristics of the study areas and populations, the methods of case ascertainment, the validation of the screening instruments, and the results of a pilot study.
目前尚无关于社区慢性对称性多神经病(CSP)患病率及其他流行病学特征的数据。本研究旨在评估意大利两个不同地区明确界定的老年人群(55岁及以上)中CSP的患病率及危险因素。邀请了在这两个地区工作的35名全科医生对前来咨询的患者进行随机抽样访谈。他们使用了一份经过预测试的问卷,该问卷聚焦于多神经病的特定症状、CSP的常见危险因素以及当前的药物治疗情况。对筛查症状问题给出肯定回答的患者由神经科医生进行进一步的临床评估。文中详细介绍了研究地区和人群的一般特征、病例确定方法、筛查工具的验证以及一项试点研究的结果。