Tohyama J, Inagaki M, Koeda T, Ohno K, Takeshita K
Division of Child Neurology, Faculty of Medicine, Tottori University, Yonago, Japan.
Neuroradiology. 1993;35(7):553-5. doi: 10.1007/BF00588723.
Computed tomography and magnetic resonance imaging (MRI) were used to examine three male siblings with nephrogenic diabetes insipidus (NDI). The two elder brothers had varying degrees of unusual intracranial calcification; the eldest also showed involvement of the cerebral white matter on MRI. The severity of intracranial calcification was related to the time before initiation of treatment and inversely to mental ability. Brain damage and mental retardation in NDI may be caused by a delay in initiating treatment; early detection and treatment are important to prevent brain damage.
计算机断层扫描和磁共振成像（MRI）被用于检查三名患有肾性尿崩症（NDI）的男性同胞。两个哥哥有不同程度的异常颅内钙化；最大的哥哥在MRI上还显示脑白质受累。颅内钙化的严重程度与开始治疗前的时间有关，与智力呈负相关。NDI中的脑损伤和智力迟钝可能是由于开始治疗延迟所致；早期检测和治疗对于预防脑损伤很重要。
