Harris M G, Buttino L M, Chan J C, Wang M
Morton D. Sarver Laboratory for Contact Lens and Corneal Research, School of Optometry, University of California, Berkeley.
Optom Vis Sci. 1993 Sep;70(9):739-42. doi: 10.1097/00006324-199309000-00010.
Ultraviolet (UV) radiation has been proposed as an alternative method for contact lens disinfection. In order for UV radiation to be considered a viable contact lens disinfection method, its effects on lens polymers and parameters must be minimal. To evaluate this, soft contact lenses from each of the four FDA categories, soft lenses with handling tints, and rigid gas permeable (RGP) lenses were exposed to UV radiation in a controlled laboratory setting and their parameters measured. After 20 h of UV exposure, we found statistically significant changes in at least one parameter for each lens type evaluated. Most of these changes were small and within the error of measurement and, therefore, were not considered clinically significant. However, the group 2 soft lenses showed an increase in all four measured parameters--power, center thickness, diameter, and water content. These changes may have an impact on lens fitting characteristics and performance. Other than these changes for group 2 soft lenses, 20 h of UV exposure appeared to have little clinical effect on the contact lenses evaluated. This suggests that UV radiation may prove to be a feasible alternative method of disinfection for most types of contact lenses.
紫外线(UV)辐射已被提议作为隐形眼镜消毒的一种替代方法。为了使紫外线辐射被视为一种可行的隐形眼镜消毒方法,其对镜片聚合物和参数的影响必须最小。为了评估这一点,在可控的实验室环境中,将来自美国食品药品监督管理局(FDA)四类中的每一类软性隐形眼镜、带有操作色标的软性隐形眼镜以及硬性透气性(RGP)隐形眼镜暴露于紫外线辐射下,并测量它们的参数。在紫外线暴露20小时后,我们发现所评估的每种镜片类型至少有一个参数发生了具有统计学意义的变化。这些变化大多很小且在测量误差范围内,因此不被认为具有临床意义。然而,第2组软性隐形眼镜在所有四个测量参数——屈光度、中心厚度、直径和含水量上均有所增加。这些变化可能会对镜片的适配特性和性能产生影响。除了第2组软性隐形眼镜的这些变化外,20小时的紫外线暴露似乎对所评估的隐形眼镜几乎没有临床影响。这表明紫外线辐射可能被证明是大多数类型隐形眼镜一种可行的替代消毒方法。