Harris M G, Gan C M, Grant T, Lycho T, Holden B A
Morton D. Sarver Laboratory for Contact Lens and Corneal Research, School of Optometry, University of California, Berkeley.
Optom Vis Sci. 1993 Oct;70(10):843-8. doi: 10.1097/00006324-199310000-00012.
We evaluated the effect of repeated microwave irradiation on soft contact lens parameters to determine if microwave disinfection affects soft lens polymers or parameters. Ten factory-sealed lenses from each of the four FDA categories were placed in Ciba AOsept cases which were filled with 13 ml of sterile unpreserved saline. The cases were placed in a 10-cm diameter circle on the rotating plate of a standard 2450 MHz 650 W microwave oven and exposed to repeated 5-min cycles of microwave irradiation. The lens parameters, including back vertex power, back optic zone radius, diameter, thickness and water content, were measured over a period of 200 cycles to simulate over 6 months of daily disinfection. The postirradiation measurements were compared to baseline measurements taken before microwave exposure. We found statistically significant changes in many lens parameters, but all were small and few were clinically significant. These findings indicate that microwave disinfection does not have a clinically significant effect on the parameters of most unworn soft contact lenses. Further studies are needed to determine the long-term effects of microwave disinfection on worn soft contact lenses.
我们评估了重复微波照射对软性隐形眼镜参数的影响，以确定微波消毒是否会影响软性隐形眼镜的聚合物或参数。从美国食品药品监督管理局（FDA）的四个类别中各选取10个工厂密封的镜片，放入装满13毫升无菌无防腐剂生理盐水的汽巴AOsept护理盒中。将护理盒放置在标准2450兆赫650瓦微波炉的旋转盘上直径为10厘米的圆圈内，进行重复5分钟的微波照射循环。在200个循环周期内测量镜片参数，包括后顶点屈光力、后光学区半径、直径、厚度和含水量，以模拟超过6个月的每日消毒情况。将照射后的测量结果与微波照射前的基线测量结果进行比较。我们发现许多镜片参数有统计学上的显著变化，但所有变化都很小，只有少数具有临床意义。这些发现表明，微波消毒对大多数未佩戴的软性隐形眼镜的参数没有临床显著影响。需要进一步研究以确定微波消毒对已佩戴的软性隐形眼镜的长期影响。
