持久性豆状角化过度症表皮的超微结构研究
An ultrastructural study of the epidermis in hyperkeratosis lenticularis perstans.
作者信息
Ikai K, Murai T, Oguchi M, Takigawa M, Komura J, Ofuji S
出版信息
Acta Derm Venereol. 1978;58(4):363-5.
A 60-year-old Japanese man contracted hyperkeratosis lenticularis perstans (Flegel). Biopsy specimens of the keratotic papules on the dorsa of the feet were studied with electron microscopy. An increase in the number of membrane coating granules, keratohyalin granules and tonofilaments was the most prominent feature of the keratinocytes underlying the keratotic papule. However, in the area just above the cone-shaped dermal infiltration, membrane coating granules were absent and keratohyalin granules and tonofilaments were poorly developed.
一名60岁的日本男性患持久性豆状角化过度症（弗莱格病）。对其足部背侧角化丘疹的活检标本进行了电子显微镜研究。膜被颗粒、透明角质颗粒和张力细丝数量增加是角化丘疹下方角质形成细胞最显著的特征。然而，在锥形真皮浸润上方的区域，膜被颗粒缺失，透明角质颗粒和张力细丝发育不良。
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