Lidocaine 2.5%/prilocaine 2.5% EMLA cream.

EMLA cream is a topical emulsion composed of prilocaine and lidocaine, produced complete anesthesia of intact skin following application. For the optimum effect, EMLA cream must be applied and covered with an occlusive dressing for 60 minutes prior to the procedure. This limits its use in emergency situations. However, in most situations where procedures are anticipated, EMLA can be applied in advance, including outpatient surgery. Furthermore, if the procedure is a venipuncture, multiple sites should be prepared in case one's initial attempt is unsuccessful. EMLA has been used in children of all ages and provides significant pain relief for venipunctures and lumbar punctures; it is being investigated in children for intramuscular injections and circumcision.