两种澳大利亚有袋动物睾丸中的精氨酸加压素和催产素样肽。

Arginine vasopressin- and oxytocin-like peptides in the testis of two Australian marsupials.

作者信息

Bathgate R A, Sernia C, Gemmell R T

机构信息

Department of Physiology and Pharmacology, University of Queensland, St. Lucia, Australia.

出版信息

Peptides. 1993 Jul-Aug;14(4):701-5. doi: 10.1016/0196-9781(93)90100-u.

DOI:10.1016/0196-9781(93)90100-u

PMID:8234012

Abstract

High performance liquid chromatography (HPLC) and specific radioimmunoassay (RIA) for arginine vasopressin (AVP), mesotocin (MT), and oxytocin (OT) were used to identify and quantify these peptides in the testis of the brushtail possum (Trichosurus vulpecula) and the northern brown bandicoot (Isoodon macrourus). Arginine vasopressin (0.092 +/- 0.041 ng/g) and MT (0.198 +/- 0.089 ng/g), but not OT, were found in the possum testis, while the bandicoot testis contained AVP (0.061 ng/g), MT (0.108 +/- 0.024 ng/g), and OT (0.114 +/- 0.053 ng/g). The values correlate well with those reported for AVP- and OT-like peptides in the testis of eutherian mammals. It was concluded that there are neurohypophysial peptides present in the marsupial testis.

摘要

采用高效液相色谱法（HPLC）和精氨酸加压素（AVP）、中催产素（MT）及催产素（OT）的特异性放射免疫分析法（RIA），对帚尾袋貂（Trichosurus vulpecula）和北褐袋狸（Isoodon macrourus）睾丸中的这些肽进行鉴定和定量分析。在袋貂睾丸中发现了精氨酸加压素（0.092±0.041纳克/克）和MT（0.198±0.089纳克/克），但未发现OT，而袋狸睾丸中含有AVP（0.061纳克/克）、MT（0.108±0.024纳克/克）和OT（0.114±0.053纳克/克）。这些值与真兽类哺乳动物睾丸中AVP和OT样肽的报道值高度相关。研究得出结论，有袋类动物睾丸中存在神经垂体肽。