Podwysocki B, Simon K, Gładysz A
Katedry i Zakładu Analityki Medycznej, Wrocławiu.
Pol Tyg Lek. 1993;48(11-13):268-70.
Differential value of ACE activity and acid alpha 1-glycoprotein was evaluated in the selected liver and biliary tract diseases. The study involved 75 patients divided into 4 subgroups, according to the character of their disease: patients with the acute viral hepatitis, chronic viral hepatitis, liver cirrhosis, and cholelithiasis. It was found that ACE activity was significantly increased in all pathologies involving liver parenchyma, and normal in patients with extrahepatic cholestasis. It was also shown that simultaneous assays of ACE and acid < alpha 1-glycoprotein may serve as a sensitive test differentiating jaundice in parenchymal hepatic diseases from that in the course of extrahepatic pathology.
在选定的肝脏和胆道疾病中评估了血管紧张素转换酶(ACE)活性和酸性α1-糖蛋白的差异值。该研究纳入了75例患者,根据疾病特征分为4个亚组:急性病毒性肝炎患者、慢性病毒性肝炎患者、肝硬化患者和胆石症患者。结果发现,在所有累及肝实质的病变中,ACE活性显著升高,而肝外胆汁淤积患者的ACE活性正常。研究还表明,同时检测ACE和酸性α1-糖蛋白可作为一种敏感的检测方法,用于区分实质性肝病引起的黄疸与肝外病变过程中的黄疸。