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以色列一个针对年轻人的十年队列中精神障碍的流行病学研究。

An epidemiological study of mental disorders in a 10-year cohort of young adults in Israel.

作者信息

Levav I, Kohn R, Dohrenwend B P, Shrout P E, Skodol A E, Schwartz S, Link B G, Naveh G

机构信息

Social Psychiatric Research Unit, New York State Psychiatric Institute, New York.

出版信息

Psychol Med. 1993 Aug;23(3):691-707. doi: 10.1017/s0033291700025472.

Abstract

This is an overview of a two-phase epidemiological study of mental disorders among young adults in a ten-year birth cohort (1949-58) conducted in Israel. A sample of 4914 Israel-born offspring of Jewish immigrants was obtained by full probability sampling procedures and screened for caseness using psychometric symptom scales from the Psychiatric Epidemiology Research Interview (PERI). Those screened positive and almost a fifth of the negatives (N = 2741) were interviewed by psychiatrists using the Schedule for Affective Disorders and Schizophrenia, Israel version (SADS-I), in order to determine prevalence rates of specific disorders as defined by the Research Diagnostic Criteria (RDC). The completion rates for each interview phase were 94.5% and 90.7% respectively. Six-month prevalence rates are presented by gender, ethnic origin, and education. Approximately one-fifth of the birth cohort met current RDC criteria for a disorder at the definite level, excluding the RDC category of 'other psychiatric disorder'. Generalized anxiety disorder and major depressive disorder were the most commonly found types. The striking findings centre on alcoholism and drug use disorder which were exceedingly rare, and the unusually similar rates of major depression for males and females. The results from this study are discussed in comparison with those obtained from other epidemiological studies.

摘要

这是对以色列一项针对一个十年出生队列(1949 - 1958年)的年轻成年人精神障碍进行的两阶段流行病学研究的概述。通过完全概率抽样程序获取了4914名在以色列出生的犹太移民后代样本,并使用来自《精神疾病流行病学研究访谈》(PERI)的心理测量症状量表对病例进行筛查。那些筛查呈阳性的人以及近五分之一的阴性者(N = 2741)由精神科医生使用《情感障碍与精神分裂症量表》以色列版(SADS - I)进行访谈,以确定由《研究诊断标准》(RDC)定义的特定障碍的患病率。每个访谈阶段的完成率分别为94.5%和90.7%。按性别、种族出身和教育程度列出了六个月患病率。在排除“其他精神障碍”这一RDC类别后,约五分之一的出生队列符合当前RDC明确水平的障碍标准。广泛性焦虑障碍和重度抑郁症是最常见的类型。显著的发现集中在酗酒和药物使用障碍极为罕见,以及男性和女性重度抑郁症的患病率异常相似。将本研究的结果与其他流行病学研究的结果进行了比较讨论。

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