Pérez C, Pérez J, Oddó D, Labarca J, Guzmán S, Acuña G, León E D
Departamento de Medicina Interna, Hospital Clínico P Universidad Catolica de Chile, Santiago.
Rev Med Chil. 1993 Jan;121(1):65-9.
A twenty nine year old male homosexual presented with malaise, weight loss, fever and profuse sweating. An ill defined abdominal mass was found during physical examination in the right lower quadrant and chest X rays disclosed a pleural effusion. HIV antibodies and hepatitis B surface antigen were positive and immunological parameters were altered. Light and electron microscopic examination of operative biopsies of the abdominal mass revealed the presence of Histoplasma capsulatum. Treatment with Amphotericin B was started with a favorable response and the patient was discharged. He was readmitted with a septic shock and died. Necropsy showed pulmonary histoplasmosis. This is the first case of disseminated histoplasmosis in a patient with AIDS described in Chile.
一名29岁的男性同性恋者出现全身不适、体重减轻、发热和大量出汗。体格检查时在右下腹发现一个边界不清的腹部肿块,胸部X线显示有胸腔积液。HIV抗体和乙肝表面抗原呈阳性,免疫参数改变。对腹部肿块手术活检进行光镜和电镜检查发现荚膜组织胞浆菌。开始用两性霉素B治疗,反应良好,患者出院。他再次入院时发生感染性休克并死亡。尸检显示有肺组织胞浆菌病。这是智利报道的首例艾滋病患者播散性组织胞浆菌病。