Hawley R S, Theurkauf W E
Department of Genetics, University of California, Davis 95616.
Trends Genet. 1993 Sep;9(9):310-7. doi: 10.1016/0168-9525(93)90249-h.
The segregation of achiasmate chromosome pairs at meiosis I is not brought about by a single 'distributive system' as previously thought, but rather by two separate mechanisms. One system uses the pairing of proximal heterochromatic sequences to mediate the segregation of achiasmate homologs-an observation that, at long last, defines a function for heterochromatin. The other system facilitates the segregation of heterologous chromosomes, by an as yet undiscovered mechanism.
减数分裂I期无交叉染色体对的分离并非如之前所认为的那样由单一的“分配系统”导致,而是由两种独立机制引起。一种系统利用近端异染色质序列的配对来介导无交叉同源染色体的分离——这一观察结果终于确定了异染色质的一种功能。另一种系统通过一种尚未发现的机制促进异源染色体的分离。