Chen X K, Zhang R Y, Zhang Z L, Jiang T Y, Wang B
School of Pharmaceutical Science, Beijing Medical University.
Yao Xue Xue Bao. 1993;28(5):352-7.
Two new saikosaponins of oleanane type were isolated from the roots of Bupleurum smithii Wolff, collected in Minhe County, Qinghai, namely saikosaponin k (VIb) and saikosaponin 1 (VIII). Their structures were elucidated on the basis of spectral analysis of UV, IR, 1HNMR, 13CNMR and FAB-MS. Saikosaponin k (VIb) was identified as 3 beta, 16 beta, 23,28-tetrahydroxyoleana-11,13(18)-dien-3-O-beta-D-xylopyranosyl-(1-->2)-beta- D-glucopyranosyl-(1-->3)-beta-D-fucopyranoside, and saikosaponin 1 (VIII) as 3 beta, 16 alpha, 23,28,30-pentahydroxyoleana-11,13(18)-dien-3-O-beta-D- glucopyranosyl-(1-->3)-beta-D-fucopyranoside, respectively.
从采自青海民和县的柴胡（Bupleurum smithii Wolff）根部分离得到两种新的齐墩果烷型柴胡皂苷，即柴胡皂苷k（VIb）和柴胡皂苷l（VIII）。通过紫外光谱（UV）、红外光谱（IR）、核磁共振氢谱（1HNMR）、核磁共振碳谱（13CNMR）和快原子轰击质谱（FAB-MS）等光谱分析确定了它们的结构。柴胡皂苷k（VIb）被鉴定为3β，16β，23，28-四羟基齐墩果-11，13（18）-二烯-3-O-β-D-吡喃木糖基-（1→2）-β-D-吡喃葡萄糖基-（1→3）-β-D-吡喃岩藻糖苷，柴胡皂苷l（VIII）被鉴定为3β，16α，23，28，30-五羟基齐墩果-11，13（18）-二烯-3-O-β-D-吡喃葡萄糖基-（1→3）-β-D-吡喃岩藻糖苷。
