Liu D, Kahn M
Doheny Eye Institute, Los Angeles, CA 90033.
Am J Ophthalmol. 1993 Nov 15;116(5):548-56. doi: 10.1016/s0002-9394(14)73195-2.
We performed a study on six fresh cadavers to measure the subarachnoid pressure of the optic nerve and to determine its relationship to intracranial pressure. A lateral orbitotomy via a coronal flap was used to expose the optic nerve. Various intracranial pressures were achieved by saline infusion through a ventriculostomy. The subarachnoid pressure of the optic nerve was measured at 5 and at 25 mm posterior to the globe under conditions of the created intracranial pressure. The effectiveness of optic nerve sheath decompression performed by two standardized surgical techniques was determined experimentally and by theoretic calculations; the role of the bulbous portion of the optic nerve was assessed experimentally. Measurements of the subarachnoid pressure of the optic nerve showed interindividual variation and a linear relationship with the intracranial pressure. Surgical decompression through a 3 x 5-mm window was more effective than were three linear 5-mm incisions. The bulbous portion of the optic nerve was found to have an important role in cerebrospinal fluid circulation.
我们对六具新鲜尸体进行了一项研究，以测量视神经的蛛网膜下腔压力，并确定其与颅内压的关系。通过冠状皮瓣进行外侧眶切开术以暴露视神经。通过脑室造瘘术注入生理盐水来实现不同的颅内压。在设定的颅内压条件下，在眼球后方5毫米和25毫米处测量视神经的蛛网膜下腔压力。通过实验和理论计算确定了两种标准化手术技术进行视神经鞘减压的有效性；通过实验评估了视神经球部的作用。对视神经蛛网膜下腔压力的测量显示个体间存在差异，且与颅内压呈线性关系。通过3×5毫米窗口进行手术减压比三个5毫米线性切口更有效。发现视神经球部在脑脊液循环中起重要作用。
