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抗菌药物组合。III. 12株铜绿假单胞菌和12株变形杆菌属菌株对磺胺甲恶唑+甲氧苄啶(复方新诺明)、多粘菌素以及复方新诺明与多粘菌素组合的体外敏感性。

Combinations of antimicrobial agents. III. The in vitro sensitivity of 12 strains of Pseudomonas aeruginosa and 12 strains of proteus species ot sulphamethoxazole + trimethoprim (co-trimoxazole), polymyxins and combinations of co-trimoxazole and polymyxins.

作者信息

Kuipers J S

出版信息

Arch Chir Neerl. 1976;28(2):91-9.

PMID:823875
Abstract

The sensitivity of 12 strains of Pseudomonas aeruginosa and of 12 strains of Proteus species to co-trimoxazole, polymyxins and combinations of co-trimoxazole and polymyxins was determined by disc and tray methods. It was found that all strains were sensitive to the combinations of co-trimoxazole and polymyxins. The disc study of the strains of Ps. aeruginosa revealed a typical image with many strains. The tray study gave a typical image with two strains of Proteus species. The two images are briefly discussed. The synergistic action of co-trimoxazole and polymyxins may well offer therapeutic possibilities.

摘要

采用纸片法和试管法测定了12株铜绿假单胞菌及12株变形杆菌属细菌对复方新诺明、多粘菌素以及复方新诺明与多粘菌素联合用药的敏感性。结果发现,所有菌株对复方新诺明与多粘菌素的联合用药均敏感。对铜绿假单胞菌菌株的纸片法研究显示,许多菌株呈现出典型的图像。对变形杆菌属的两株菌株进行的试管法研究也得到了典型的图像。文中简要讨论了这两种图像。复方新诺明与多粘菌素的协同作用很可能提供治疗的可能性。

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Arch Chir Neerl. 1976;28(2):91-9.
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