Magnier S, Hanania G, Saudemont J P, Guillemaut P, Baragan J, Scebat L, Gerbaux A
Arch Mal Coeur Vaiss. 1976 Jan;69(1):59-69.
42 patients who were given the diagnosis of obstructive cardiomyopathy (OCM) on the basis of a basal left intraventricular systolic gradient equal to or in excess of 20 mmHg were divided into two groups, according to the angiocardiographic appearances (in the right anterior oblique projection) of the left ventricular cavity during systole. In 20 cases the appearances were those of a typical obstructive cardiomyopathy. In the other 22, despite the presence of a fairly large left intraventricular gradient, the appearances on angiocardiography were closest to those described for the non-obstructive cardiomyopathies with diffuse myocardial hypertrophy. These two groups were compared in the quest for a difference between the clinical, radiological, electrocardiographic, phonomechanographic, and haemodynamic picture on the one hand, and the appearances at angiography on the other. These two groups can only be separated by the mean value of the left intraventricular systolic gradient established under basal conditions; this is greater when the angiographic picture is less characteristic. However, the value of this gradient is shown by the positive correlation between the figure for the gradient and that for the left ventricular ejection time, as determined from external phonomecanographic measurements and from the catheter on the left side. This determination confirms the existance of obstruction to the outflow and the diagnosis of obstructive cardiomyopathy, even when the angiographic appearances are not typical.
42例根据基础状态下左心室内收缩期梯度等于或超过20mmHg而被诊断为梗阻性心肌病(OCM)的患者,根据收缩期左心室腔的心血管造影表现(右前斜位)被分为两组。20例表现为典型的梗阻性心肌病。另外22例,尽管存在相当大的左心室内梯度,但心血管造影表现最接近那些描述的伴有弥漫性心肌肥厚的非梗阻性心肌病。对这两组进行比较,以探寻一方面临床、放射学、心电图、心音图和血流动力学表现与另一方面心血管造影表现之间的差异。这两组只能通过基础状态下确定的左心室内收缩期梯度的平均值来区分;当心血管造影表现不太典型时,该平均值更大。然而,该梯度的值通过梯度数值与从外部心音图测量和左侧导管测定的左心室射血时间数值之间的正相关得以体现。这一测定证实了即使心血管造影表现不典型时也存在流出道梗阻及梗阻性心肌病的诊断。