Tagawa Y, Seki T, Shiro T, Nakagawa T, Wakabayashi M, Ito T, Yamamura H, Koreeda C, Naitoh Y, Okuno H
3rd Dept. of Internal Medicine, Kansai Medical University.
Gan To Kagaku Ryoho. 1993 Nov;20(14):2217-20.
A 74-year-old man was diagnosed as hepatocellular carcinoma (HCC) in the area of S6-7 with tumor thrombus continuously developed from hepatic vein to inferior vena cava (IVC). AFP value remained high despite two transcatheter arterial embolizations with adriamycin, mitomycin and Lipiodol (Lp-TAE). The AFP value gradually decreased two weeks after oral administration of UFT. Nine months after, the AFP level was 26.4 ng/ml and the tumor thrombus in the IVC disappeared. The size of the main tumor did not change. This case suggests Lp-TAE and UFT are useful for suppressing the growth of the main tumor and to extinguish the tumor thrombus.
一名74岁男性被诊断为S6-7区域的肝细胞癌（HCC），肿瘤血栓从肝静脉持续发展至下腔静脉（IVC）。尽管进行了两次使用阿霉素、丝裂霉素和碘油（Lp-TAE）的经导管动脉栓塞术，但甲胎蛋白（AFP）值仍居高不下。口服优福定（UFT）两周后，AFP值逐渐下降。九个月后，AFP水平为26.4 ng/ml，IVC中的肿瘤血栓消失。主要肿瘤的大小没有变化。该病例表明，Lp-TAE和UFT可有效抑制主要肿瘤的生长并消除肿瘤血栓。
