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[肝癌患者口服优福定及经动脉栓塞化疗后下腔静脉内肿瘤血栓消失;病例报告]

[Vanishing tumor thrombus in IVC after oral administration of UFT and TAE in a patient with HCC; a case report].

作者信息

Tagawa Y, Seki T, Shiro T, Nakagawa T, Wakabayashi M, Ito T, Yamamura H, Koreeda C, Naitoh Y, Okuno H

机构信息

3rd Dept. of Internal Medicine, Kansai Medical University.

出版信息

Gan To Kagaku Ryoho. 1993 Nov;20(14):2217-20.

PMID:8239688
Abstract

A 74-year-old man was diagnosed as hepatocellular carcinoma (HCC) in the area of S6-7 with tumor thrombus continuously developed from hepatic vein to inferior vena cava (IVC). AFP value remained high despite two transcatheter arterial embolizations with adriamycin, mitomycin and Lipiodol (Lp-TAE). The AFP value gradually decreased two weeks after oral administration of UFT. Nine months after, the AFP level was 26.4 ng/ml and the tumor thrombus in the IVC disappeared. The size of the main tumor did not change. This case suggests Lp-TAE and UFT are useful for suppressing the growth of the main tumor and to extinguish the tumor thrombus.

摘要

一名74岁男性被诊断为S6-7区域的肝细胞癌(HCC),肿瘤血栓从肝静脉持续发展至下腔静脉(IVC)。尽管进行了两次使用阿霉素、丝裂霉素和碘油(Lp-TAE)的经导管动脉栓塞术,但甲胎蛋白(AFP)值仍居高不下。口服优福定(UFT)两周后,AFP值逐渐下降。九个月后,AFP水平为26.4 ng/ml,IVC中的肿瘤血栓消失。主要肿瘤的大小没有变化。该病例表明,Lp-TAE和UFT可有效抑制主要肿瘤的生长并消除肿瘤血栓。

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